Dario Braga


Mechanochemical preparation of cocrystals Chem Soc Rev 2013

Review on mechanochemistry and cocrystals – also abundantly cited
Dario Braga,* Lucia Maini and Fabrizia Grepioni
The preparation of co-crystals via mechanochemistry combines the quest for clean and green processes with the investigation of multicomponent new materials, among the currently most fashionable systems in the crystal engineering field: the physico-chemical properties of the components add, merge or transform when co-crystals are formed, giving rise to potentially improved performance in ‘‘old’’ solid-state chemistry fields, as in the pharmaceutical industry field, where they represent a way to obtain new formulations and to improve the properties (solubility, thermal stability, compressibility, etc.) of both new and existing drugs.

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