The relevance of crystal forms in the pharmaceutical field: sword of Damocles or innovation tools?
Dario Braga, Lucia Casali and Fabrizia Grepioni Department of Chemistry G. Ciamician, University of Bologna, Via Selmi 2, 40126 Bologna, Italy. Abstract: This review is aimed to provide to an “educated but non-expert” readership an overview of the scientific, commercial, and ethical importance of investigating crystalline forms (polymorphs, hydrates and co-crystals) of active pharmaceutical ingredients […]
Steps Towards a Nature Inspired Inorganic Crystal Engineering
Fabrizia Grepioni,* Lucia Casali, Cecilia Fiore, Luca Mazzei, Renren Sun, Oleksii Shemchukd and Dario Braga* Crystal engineering is used for properties modification of organic solids via cocrystallization with inorganic salts, to tackle chiral resolution, enzyme inhibition and antimicrobial resistance within a frame of cross-disciplinary scientific expertise.
Crystal engineering: from promise to delivery
Twenty years ago, I wrote a Chem. Commun. feature article entitled ‘‘Crystal Engineering: where from?Where to?’’: an update is in order. In this Highlight I argue that molecular crystal engineering, one of theareas of fast development of the field, has definitely reached the stage of ‘‘delivering the goods’’: newfunctional materials assembled via non-covalent interactions and/or […]
Scientific papers published in 2023
In the following the complete references to scientific papers published in 2023
Scientific papers published in 2022
in the following the complete references uof the crystal engineeering papers published in 2022
Scientific papers published in 2021
publications on crystal engineering results published in 2021
Mechanochemical preparation of cocrystals Chem Soc Rev 2013
Review on mechanochemistry and cocrystals – also abundantly cited Dario Braga,* Lucia Maini and Fabrizia GrepioniThe preparation of co-crystals via mechanochemistry combines the quest for clean and green processes with the investigation of multicomponent new materials, among the currently most fashionable systems in the crystal engineering field: the physico-chemical properties of the components add, merge […]
Mechanochemistry: opportunities for new and cleaner synthesis Chem Rev 2012
This is our most cited paper to date – Co-authored by Stuart L. James,*a Christopher J. Adams,b Carsten Bolm,c Dario Braga,d Paul Collier,e Tomislav Frisˇcˇic´, f Fabrizia Grepioni,d Kenneth D. M. Harris,g Geoff Hyett,h William Jones,f Anke Krebs,c James Mack,i Lucia Maini,d A. Guy Orpen,b Ivan P. Parkin,j William C. Shearouse,i Jonathan W. Steedk and […]